- To prevent lost time: on using the most effective medication first, not last
- ADHD, Accidents, and Premature Death
- How lithium helps prevent suicide: one patient’s experience
- Psychopharmacology Made Simple: What’s it like when an SSRI[i] works?
- Psychopharmacology Made Simple: What’s it like when Wellbutrin works?
Author Archives: John C. Raiss
Joseph Goldberg has written an important article for clinicians who treat patients with mood disorders. Goldberg JF. Should we reserve big gun antimanic drugs for only big gun manias? Bipolar Disord. 2018; 20:7–8. https://doi.org/10.1111/bdi.12597 He suggests, writing primarily about olanzapine, … Continue reading
Occasionally insurance companies make doctors fill out forms for medications not on their formularies, and on the form will be a statement that asks the doctor to check a box if a ‘standard review timeline’ of 72 hours might seriously … Continue reading
How lithium helps prevent suicide: a patient’s experience Lithium is one of the most effective anti-suicide medications psychiatrists have to treat patients with mood disorders. http://www.bmj.com/content/346/bmj.f3646 How it works is unknown. [i] Recently, a patient of mine … Continue reading
Psychopharmacology Made Simple: What’s it like when an SSRI works? What benefit can one expect from a medication? While it’s easy enough to find information online about side effects and diagnostic indications (approved uses), it’s much more difficult to learn … Continue reading
Wellbutrin (bupropion) works quite differently from SSRIs such as Lexapro (escitalopram), the subject of a previous blog post. How does it work? Per UpToDate, “like other antidepressants the mechanism of bupropion’s activity is not fully understood”.  Clinically, it’s … Continue reading
Hypomanic states are rarely observed by the psychiatric clinician. Bipolar patients are much more commonly depressed (according to Judd et al, bipolar II patients spent only 1.3% of the time in hypomania over 13 years of follow-up). http://jamanetwork.com/journals/jamapsychiatry/fullarticle/207252 accessed 1/14/17 … Continue reading
The English have a somewhat more relaxed attitude towards drinking in pregnancy than we do in the States. From the RCOG: “It is recommended that you do not drink alcohol during the first three months of pregnancy. Drinking small amounts … Continue reading
An important review article and meta-analysis, Early Treatment Responses of Selective Serotonin Reuptake Inhibitors (SSRIs) and clomipramine in pediatric OCD was published in the Journal of the American Academy of Child and Adolescent Psychiatry (October, 2016, p 851-859). http://www.jaacap.com/article/S0890-8567(16)31160-1/fulltext The … Continue reading
Too often, when I ask patients if they smoke cigarettes, I hear, “Oh, only 2 or 3 a day”, as if, not a problem, no big deal, like saying, “when I play Russian roulette, there’s only one bullet in the … Continue reading
All animals sleep, even flies (research with the fruit fly Drosophila revealed the presence of clock genes). All mammals have REM (rapid eye movement) and non-REM sleep. Human infants sleep 16 hours/day (if their parents are lucky); adults sleep 8 … Continue reading